Polygenic Risk in Clinical Practice

Polygenic scores (PGS) are a new type of genetic test that can provide people with information about their chances of developing a health condition. PGS testing is not yet routinely used in healthcare and there is limited research on their clinical utility in improving health outcomes.

Our team is leading implementation of PGS in clinical practice through several studies that aim to:

  • Develop best practice for providing PGS information

  • Evaluate the psychological and behavioural impact of PGS testing

  • Develop education and training for clinicians on the use of PGS

  • Evaluate pathways for laboratory accreditation of PGS

RESEARCH STUDIES

Personalised Risk Scores for Melanoma Management (PRiSMM)

Polygenic risk score (PRS) education for genetic health professionals

Pathway for laboratory accreditation of PGS

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Mainstreaming genomic testing