Personalised Risk Scores for Melanoma Management (PRiSMM)
About melanoma risk:
There are many factors that contribute to a person’s chances of having melanoma, including genetics, clinical characteristics, and lifestyle factors. We can now estimate a person’s chances of having melanoma by combining all the known risk factors for the condition. This is called personalised risk. Using personalised risk, we can find people with an increased chance of melanoma and discuss appropriate surveillance and screening.
About PRiSMM:
Currently, testing for personalised risk is not available in any clinical setting. PRiSMM aims to support the use of personalised risk for melanoma in clinic by:
Creating new tools to communicate personalised risk
Assessing the psychological and behavioural impact of receiving personalised melanoma risk
This research is a sub-study of the Australian Centre for Excellence in Melanoma Imaging and Diagnosis clinical trial.
Contact us: prismm@uq.edu.au
Research outputs
Lee, K. J., Betz-Stablein, B., Stark, M. S., Janda, M., McInerney-Leo, A. M., Caffery, L. J., ... & Soyer, H. P. (2022). The future of precision prevention for advanced melanoma. Frontiers in Medicine, 8, 818096. https://doi.org/10.3389/fmed.2021.818096
Bhave, P., Wong, J., McInerney‐Leo, A., Cust, A. E., Lawn, C., Janda, M., & Mar, V. J. (2023). Management of cutaneous melanoma in Australia: a narrative review. Medical Journal of Australia. https://www.mja.com.au/system/files/issues/218_09/mja251910.pdf
Wallingford, C. K., Maas, E. J., Howard, A., DeBortoli, E., Bhanja, D., Lee, K., ... & McInerney‐Leo, A. M. (2024). MITF E318K: A rare homozygous case with multiple primary melanoma. Pigment Cell & Melanoma Research, 37(1), 68-73. https://doi.org/10.1111/pcmr.13122
Funding
This study is funded by the:
National Health and Medical Research Council Investigator Grant
The Australian Melanoma Research Foundation